leukotriene e4 การใช้

• 5-( " S " )-HETE family members share a common receptor target for stimulating cells that differs from and receptors targeted by the other major products of ALOX5, i . e ., leukotriene B4, leukotriene C4, leukotriene D4, leukotriene E4, lipoxin A4, and lipoxin B4; members of the 5-( " S " )-HETE family stimulate cells primarily by binding and thereby activating a dedicated G protein-coupled receptor, the oxoeicosanoid receptor 1 or OXER1 ( also termed OXE, OXE-R, hGPCR48, HGPCR48, or R527 receptor ); OXER1's gene is sometimes termed OXE1.